Guru Ownership Trend
Guru Analysis for Ionis Pharmaceuticals, Inc. (IONS)
Ionis Pharmaceuticals, Inc. (IONS), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q3 2025, a total of 9 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $346.47 M.
Top institutional holders include Tweedy Browne and Catherine Wood.
Notably, Tweedy Browne has expressed high conviction in this stock, allocating 16.48% of their equity portfolio to it.
Institutional sentiment is currently Slightly Bearish. This is evidenced by a $10.33 M net outflow during the quarter.
Recent activity highlights Joel Greenblatt who increased their stake by 125.2%. Conversely, Jefferies Group reduced exposure by 54.6%.
| Portfolio Manager | % Portfolio | Activity | Shares | Value | Report Date |
|---|---|---|---|---|---|
| 16.48% | Add 0.3% | 2,901,216 | $189.8 M | Q3 2025 | |
| 0.25% | Reduce -29.9% | 631,215 | $41.29 M | Q3 2025 | |
| 0.04% | Add 79.8% | 486,714 | $31.84 M | Q3 2025 | |
| 0.01% | New Buy | 43,578 | $2.85 M | Q3 2025 | |
| 0.01% | Add 125.2% | 32,152 | $2.1 M | Q3 2025 | |
| 0.01% | Add 4.4% | 12,476 | $816,180 | Q3 2025 | |
| 0.00% | Reduce -54.6% | 10,169 | $665,256 | Q3 2025 | |
| 0.00% | New Buy | 6,815 | $438,749 | Q3 2025 | |
| 0.00% | New Buy | 6,210 | $406,258 | Q3 2025 |
| Report Date | Portfolio Manager | Activity | Share Change | % Portfolio Change |
|---|
| Report Date | Portfolio Manager | Activity | Share Change | % Portfolio Change |
|---|
| Report Date | Portfolio Manager | Activity | Share Change | % Portfolio Change |
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| Portfolio Manager | Option Type | % Portfolio | Activity | Shares | Value | Report Date |
|---|
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q3 2025)
Guru Consensus (Q3 2025)
FAQs for Ionis Pharmaceuticals, Inc. (IONS)
Major holders include Tweedy Browne ($189.8 M), Catherine Wood ($41.29 M), Renaissance Technologies ($31.84 M). According to the latest reported data, 9 tracked investment managers collectively hold approximately 4.13 M shares.
According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $10.33 M, with 7 managers increasing positions and 3 managers reducing holdings.
During the most recent reporting period, 2 managers trimmed their positions, while 1 fully exited IONS. The total reported sell value was $29.97 M.
Yes, 3 managers opened new positions in IONS, and 4 increased their existing holdings. The total reported buy value was $19.64 M.