Guru Ownership Trend
Guru Analysis for Ionis Pharmaceuticals, Inc. (IONS)
Ionis Pharmaceuticals, Inc. (IONS), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q4 2025, a total of 10 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $245.52 M.
Top institutional holders include Tweedy Browne and Catherine Wood.
Notably, Tweedy Browne has expressed high conviction in this stock, allocating 15.74% of their equity portfolio to it.
Institutional sentiment is currently Bearish. This is evidenced by a $53.94 M net outflow during the quarter.
Recent activity highlights Ken Fisher who dramatically increased their stake. Conversely, Renaissance Technologies reduced exposure by 54.1%.
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q4 2025)
Guru Consensus (Q4 2025)
FAQs for Ionis Pharmaceuticals, Inc. (IONS)
Major holders include Tweedy Browne ($195 M), Catherine Wood ($33.46 M), Renaissance Technologies ($17.69 M). According to the latest reported data, 10 tracked investment managers collectively hold approximately 3.45 M shares.
According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $53.94 M, with 6 managers increasing positions and 4 managers reducing holdings.
During the most recent reporting period, 4 managers trimmed their positions, while 0 fully exited IONS. The total reported sell value was $71.84 M.
Yes, 1 managers opened new positions in IONS, and 5 increased their existing holdings. The total reported buy value was $17.91 M.
