🎉 Founding Member Beta — Join our Discord and get 3 months of Pro free. Learn more →

Ionis Pharmaceuticals, Inc.

IONS Healthcare
$73.28 $-0.54 (-0.74%)
Market Cap: $12.11 B
Gurus Holding
9
Popularity Rank
#641
% of Shares Held
1.97%
Net Activity (Q1 2026)
-$14.61 M

Guru Ownership Trend

Guru Analysis for Ionis Pharmaceuticals, Inc. (IONS)

Ionis Pharmaceuticals, Inc. (IONS), a key player in the Healthcare sector, continues to attract institutional attention.

As of Q1 2026, a total of 9 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $238.72 M.

Top institutional holders include Tweedy Browne and Renaissance Technologies (RenTech).

Notably, Tweedy Browne has expressed high conviction in this stock, allocating 13.57% of their equity portfolio to it.

Institutional sentiment is currently Slightly Bearish. This is evidenced by a $14.61 M net outflow during the quarter.

Recent activity highlights Paul Tudor Jones who dramatically increased their stake. Conversely, Catherine Wood reduced exposure by 31.7%.

Key Holders

Top 5 by Value

Recent Activity Breakdown (Q1 2026)

+$15.09 M
Total Buy Value
New Buys 0
Additions 5
-$29.7 M
Total Sell Value
Reductions 4
Sold Out 1

Guru Consensus (Q1 2026)

Based on recent activity
Net Sellers
5
Net Buyers
5

FAQs for Ionis Pharmaceuticals, Inc. (IONS)

Major holders include Tweedy Browne ($170.88 M), Renaissance Technologies (RenTech) ($22.94 M), Catherine Wood ($21.68 M). According to the latest reported data, 9 tracked investment managers collectively hold approximately 3.26 M shares.

According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $14.61 M, with 5 managers increasing positions and 5 managers reducing holdings.

During the most recent reporting period, 4 managers trimmed their positions, while 1 fully exited IONS. The total reported sell value was $29.7 M.

Yes, 0 managers opened new positions in IONS, and 5 increased their existing holdings. The total reported buy value was $15.09 M.

Portfolio Manager % Portfolio Activity Shares Value Report Date
13.57% Reduce -7.7% 2,275,625 $170.88 M Q1 2026
0.04% Add 36.7% 305,549 $22.94 M Q1 2026
0.17% Reduce -31.7% 288,716 $21.68 M Q1 2026
0.00% Reduce -0.1% 141,544 $10.63 M Q1 2026
0.02% Add 129.0% 98,968 $7.43 M Q1 2026
0.03% Add 17.2% 59,065 $4.44 M Q1 2026
0.01% Add 1217.8% 48,244 $3.62 M Q1 2026
0.00% Add 53.4% 28,783 $2.16 M Q1 2026
0.01% Reduce -4.4% 11,428 $858,129 Q1 2026
Date
Insider Name
Transaction
Value
Shares
Position / Chg
SEC Form