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Vertex Pharmaceuticals Incorporated

VRTX Healthcare
$466.1 $-3.24 (-0.69%)
Market Cap: $118.41 B
Gurus Holding
10
Popularity Rank
#434
% of Shares Held
0.49%
Net Activity (Q4 2025)
-$153.4 M

Guru Ownership Trend

Guru Analysis for Vertex Pharmaceuticals Incorporated (VRTX)

Vertex Pharmaceuticals Incorporated (VRTX), a key player in the Healthcare sector, continues to attract institutional attention.

As of Q4 2025, a total of 10 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $583.92 M.

Top institutional holders include Renaissance Technologies and Manning & Napier Group.

Institutional sentiment is currently Bearish. This is evidenced by a $153.4 M net outflow during the quarter.

Recent activity highlights Jefferies Group who increased their stake by 96.1%. Conversely, Paul Tudor Jones reduced exposure by 89.0%.

Key Holders

Top 5 by Value

Recent Activity Breakdown (Q4 2025)

+$7.2 M
Total Buy Value
New Buys 0
Additions 3
-$160.61 M
Total Sell Value
Reductions 7
Sold Out 1

Guru Consensus (Q4 2025)

Based on recent activity
Net Sellers
8
Net Buyers
3

FAQs for Vertex Pharmaceuticals Incorporated (VRTX)

Major holders include Renaissance Technologies ($228.97 M), Manning & Napier Group ($194.02 M), Cliff Asness ($65.13 M). According to the latest reported data, 10 tracked investment managers collectively hold approximately 1.25 M shares.

According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $153.4 M, with 3 managers increasing positions and 8 managers reducing holdings.

During the most recent reporting period, 7 managers trimmed their positions, while 1 fully exited VRTX. The total reported sell value was $160.61 M.

Yes, 0 managers opened new positions in VRTX, and 3 increased their existing holdings. The total reported buy value was $7.2 M.

Portfolio Manager % Portfolio Activity Shares Value Report Date
0.36% Reduce -31.4% 505,048 $228.97 M Q4 2025
2.52% Reduce -9.9% 427,603 $194.02 M Q4 2025
0.03% Reduce -11.2% 143,651 $65.13 M Q4 2025
1.43% Add 0.2% 39,148 $17.75 M Q4 2025
0.07% Add 96.1% 31,372 $14.22 M Q4 2025
0.05% Reduce -28.3% 27,488 $12.46 M Q4 2025
0.08% Add 1.7% 26,100 $11.83 M Q4 2025
0.00% Reduce -2.9% 25,218 $11.43 M Q4 2025
0.04% Reduce -1.7% 21,511 $9.75 M Q4 2025
0.00% Reduce -89.0% 5,641 $2.56 M Q4 2025
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