Guru Ownership Trend
Guru Analysis for Septerna, Inc. (SEPN)
Septerna, Inc. (SEPN), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q1 2026, a total of 3 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $4.77 M.
Top institutional holders include John Hussman and Renaissance Technologies (RenTech).
Institutional sentiment is currently Bullish. This is evidenced by a $3.11 M net inflow during the quarter.
Recent activity highlights John Hussman who opened a new position.
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q1 2026)
Guru Consensus (Q1 2026)
FAQs for Septerna, Inc. (SEPN)
Major holders include John Hussman ($2.52 M), Renaissance Technologies (RenTech) ($905,931), Cliff Asness ($369,461). According to the latest reported data, 3 tracked investment managers collectively hold approximately 158,075 shares.
According to the latest 13F reporting period, sentiment appears Bullish (Net Buying). There was a net inflow of $3.11 M, with 3 managers increasing positions and 1 managers reducing holdings.
During the most recent reporting period, 0 managers trimmed their positions, while 1 fully exited SEPN. The total reported sell value was $503,318.
Yes, 2 managers opened new positions in SEPN, and 1 increased their existing holdings. The total reported buy value was $3.61 M.