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Septerna, Inc.

SEPN Healthcare
$43.93 +$0.13 (0.30%)
Market Cap: $2.05 B
Gurus Holding
5
Popularity Rank
#1753
% of Shares Held
0.34%
Net Activity (Q2 2026)
+$971.06

Guru Ownership Trend

Guru Analysis for Septerna, Inc. (SEPN)

Septerna, Inc. (SEPN), a key player in the Healthcare sector, continues to attract institutional attention.

As of Q2 2026, a total of 5 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $6.95 M.

Top institutional holders include John Hussman and Renaissance Technologies (RenTech).

Institutional sentiment is currently Bullish. This is evidenced by a $971.06 net inflow during the quarter.

Recent activity highlights Paul Tudor Jones who opened a new position. Conversely, John Hussman reduced exposure by 40.0%.

Key Holders

Top 5 by Value

Recent Activity Breakdown (Q2 2026)

+$1.41 M
Total Buy Value
New Buys 2
Additions 2
-$1.41 M
Total Sell Value
Reductions 1
Sold Out 0

Guru Consensus (Q2 2026)

Based on recent activity
Net Sellers
1
Net Buyers
4

FAQs for Septerna, Inc. (SEPN)

Major holders include John Hussman ($2.11 M), Renaissance Technologies (RenTech) ($1.39 M), Paul Tudor Jones ($970,071). According to the latest reported data, 5 tracked investment managers collectively hold approximately 158,104 shares.

According to the latest 13F reporting period, sentiment appears Bullish (Net Buying). There was a net inflow of $971.06, with 4 managers increasing positions and 1 managers reducing holdings.

During the most recent reporting period, 1 managers trimmed their positions, while 0 fully exited SEPN. The total reported sell value was $1.41 M.

Yes, 2 managers opened new positions in SEPN, and 2 increased their existing holdings. The total reported buy value was $1.41 M.

Portfolio Manager % Portfolio Activity Shares Value Report Date
0.49% Reduce -40.0% 63,000 $2.11 M Q2 2026
0.00% Add 9.9% 41,419 $1.39 M Q2 2026
0.00% New Buy 28,966 $970,071 Q2 2026
0.00% Add 0.1% 15,397 $515,646 Q2 2026
0.00% New Buy 9,322 $312,194 Q2 2026
Date
Insider Name
Transaction
Value
Shares
Position / Chg
SEC Form