Renaissance Technologies (RenTech)'s SEPN Position Overview
Renaissance Technologies (RenTech) (via Renaissance Technologies LLC) currently holds 41,419 shares of Septerna, Inc. (SEPN) worth $1.39 M, representing 0.00% of the portfolio. First purchased in 2013-Q4, this medium-term investment has been held for 12 quarters.
Based on 13F filings, Renaissance Technologies (RenTech) has maintained a strategic position in SEPN, demonstrating sustained confidence in this investment. Largest addition occurred in Q2 2015, adding 1.04 M shares. Largest reduction occurred in Q3 2015, reducing 956,700 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies (RenTech)'s Septerna (SEPN) Holding Value Over Time
Track share changes against reported price movement
Quarterly Septerna (SEPN) Trades by Renaissance Technologies (RenTech)
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q2 2026 | +3,719 | Add 9.86% | 41,419 | $33.49 |
| Q1 2026 | +37,700 | New Buy | 37,700 | $24.03 |
| Q2 2016 | -765,600 | Sold Out | 0 | $0.00 |
| Q1 2016 | -311,600 | Reduce 28.93% | 765,600 | $30.60 |
| Q4 2015 | +622,600 | Add 136.96% | 1.08 M | $23.94 |
| Q3 2015 | -956,700 | Reduce 67.79% | 454,600 | $26.27 |
| Q2 2015 | +1.04 M | Add 275.85% | 1.41 M | $32.60 |
| Q1 2015 | +375,500 | New Buy | 375,500 | $36.17 |
| Q4 2014 | -606,800 | Sold Out | 0 | $0.00 |
| Q3 2014 | +606,800 | New Buy | 606,800 | $39.26 |
| Q1 2014 | -307,800 | Sold Out | 0 | $0.00 |
| Q4 2013 | +307,800 | New Buy | 307,800 | $35.62 |
Renaissance Technologies (RenTech)'s Septerna Investment FAQs
Renaissance Technologies (RenTech) first purchased Septerna, Inc. (SEPN) in Q4 2013, acquiring 307,800 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies (RenTech) has held Septerna, Inc. (SEPN) for 12 quarters since Q4 2013.
Renaissance Technologies (RenTech)'s largest addition to Septerna, Inc. (SEPN) was in Q2 2015, adding 1,411,300 shares worth $46.01 M.
According to the latest 13F filing for Q2 2026, Renaissance Technologies (RenTech)'s firm, Renaissance Technologies LLC, owns 41,419 shares of Septerna, Inc. (SEPN), valued at approximately $1.39 M.
As of the Q2 2026 filing, Septerna, Inc. (SEPN) represents approximately 0.00% of Renaissance Technologies (RenTech)'s publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies (RenTech)'s peak holding in Septerna, Inc. (SEPN) was 1,411,300 shares, as reported at the end of Q2 2015.