Cliff Asness's SEPN Position Overview
Cliff Asness (via Aqr Capital Management LLC) currently holds 15,397 shares of Septerna, Inc. (SEPN) worth $515,646, representing 0.00% of the portfolio. First purchased in 2012-Q4, this long-term strategic position has been held for 21 quarters.
Based on 13F filings, Cliff Asness has maintained a strategic position in SEPN, demonstrating sustained confidence in this investment. Largest addition occurred in Q3 2016, adding 216,326 shares. Largest reduction occurred in Q1 2017, reducing 508,630 shares.
Analysis based on 13F filings available since 2013 Q2
Cliff Asness's Septerna (SEPN) Holding Value Over Time
Track share changes against reported price movement
Quarterly Septerna (SEPN) Trades by Cliff Asness
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q2 2026 | +22 | Add 0.14% | 15,397 | $33.49 |
| Q1 2026 | +7,549 | Add 96.46% | 15,375 | $24.03 |
| Q4 2025 | +7,826 | New Buy | 7,826 | $27.88 |
| Q1 2017 | -508,630 | Sold Out | 0 | $0.00 |
| Q4 2016 | +82,404 | Add 19.33% | 508,630 | $41.09 |
| Q3 2016 | +216,326 | Add 103.06% | 426,226 | $42.75 |
| Q2 2016 | +141,834 | Add 208.38% | 209,900 | $36.63 |
| Q1 2016 | +49,092 | Add 258.73% | 68,066 | $30.60 |
| Q4 2015 | -1,815 | Reduce 8.73% | 18,974 | $23.93 |
| Q3 2015 | -85,909 | Reduce 80.52% | 20,789 | $26.26 |
| Q2 2015 | -88,761 | Reduce 45.41% | 106,698 | $32.60 |
| Q1 2015 | -225,800 | Reduce 53.60% | 195,459 | $36.17 |
| Q4 2014 | +198,600 | Add 89.19% | 421,259 | $36.30 |
| Q3 2014 | +103,000 | Add 86.08% | 222,659 | $39.26 |
| Q2 2014 | +20,700 | Add 20.92% | 119,659 | $42.48 |
| Q1 2014 | +28,273 | Add 40.00% | 98,959 | $36.94 |
| Q4 2013 | -6,500 | Reduce 8.42% | 70,686 | $35.62 |
| Q3 2013 | -39,118 | Reduce 33.63% | 77,186 | $34.23 |
| Q2 2013 | +116,304 | Add 0.00% | 116,304 | $34.46 |
| Q4 2012 | +122,943 | Add 0.00% | 122,943 | $27.38 |
Cliff Asness's Septerna Investment FAQs
Cliff Asness first purchased Septerna, Inc. (SEPN) in Q4 2012, acquiring 122,943 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Cliff Asness has held Septerna, Inc. (SEPN) for 21 quarters since Q4 2012.
Cliff Asness's largest addition to Septerna, Inc. (SEPN) was in Q3 2016, adding 426,226 shares worth $18.22 M.
According to the latest 13F filing for Q2 2026, Cliff Asness's firm, Aqr Capital Management LLC, owns 15,397 shares of Septerna, Inc. (SEPN), valued at approximately $515,646.
As of the Q2 2026 filing, Septerna, Inc. (SEPN) represents approximately 0.00% of Cliff Asness's publicly disclosed stock portfolio, making it one of their key holdings.
Cliff Asness's peak holding in Septerna, Inc. (SEPN) was 508,630 shares, as reported at the end of Q4 2016.