Renaissance Technologies's PRAX Position Overview
Renaissance Technologies (via Renaissance Technologies LLC) currently holds 66,230 shares of Praxis Precision Medicines, Inc. (PRAX) worth $19.52 M, representing 0.03% of the portfolio. First purchased in 2021-Q2, this medium-term investment has been held for 15 quarters.
Based on 13F filings, Renaissance Technologies has maintained a strategic position in PRAX, demonstrating sustained confidence in this investment. Largest addition occurred in Q4 2025, adding 66,230 shares. Largest reduction occurred in Q3 2024, reducing 75,433 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies's Praxis Precision Medicines (PRAX) Holding Value Over Time
Track share changes against reported price movement
Quarterly Praxis Precision Medicines (PRAX) Trades by Renaissance Technologies
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q4 2025 | +66,230 | New Buy | 66,230 | $294.74 |
| Q3 2024 | -75,433 | Sold Out | 0 | $0.00 |
| Q2 2024 | +63,329 | Add 523.21% | 75,433 | $41.36 |
| Q1 2024 | -68,700 | Reduce 85.02% | 12,104 | $61.05 |
| Q4 2023 | +15,671 | Add 24.06% | 80,804 | $22.28 |
| Q3 2023 | +21,413 | Add 48.98% | 65,133 | $25.66 |
| Q2 2023 | +18,387 | Add 72.58% | 43,720 | $0.02 |
| Q1 2023 | +1,066 | Add 4.39% | 25,333 | $0.01 |
| Q4 2022 | -5,674 | Reduce 18.95% | 24,267 | $0.04 |
| Q3 2022 | +15,448 | Add 106.59% | 29,941 | $34.03 |
| Q2 2022 | +9,706 | Add 202.76% | 14,493 | $36.78 |
| Q1 2022 | +3,914 | Add 448.34% | 4,787 | $153.12 |
| Q4 2021 | +873 | New Buy | 873 | $295.53 |
| Q3 2021 | -2,493 | Sold Out | 0 | $0.00 |
| Q2 2021 | +2,493 | New Buy | 2,493 | $274.37 |
Renaissance Technologies's Praxis Precision Medicines Investment FAQs
Renaissance Technologies first purchased Praxis Precision Medicines, Inc. (PRAX) in Q2 2021, acquiring 2,493 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies has held Praxis Precision Medicines, Inc. (PRAX) for 15 quarters since Q2 2021.
Renaissance Technologies's largest addition to Praxis Precision Medicines, Inc. (PRAX) was in Q4 2025, adding 66,230 shares worth $19.52 M.
According to the latest 13F filing for Q4 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 66,230 shares of Praxis Precision Medicines, Inc. (PRAX), valued at approximately $19.52 M.
As of the Q4 2025 filing, Praxis Precision Medicines, Inc. (PRAX) represents approximately 0.03% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies's peak holding in Praxis Precision Medicines, Inc. (PRAX) was 80,804 shares, as reported at the end of Q4 2023.