Guru Ownership Trend
Guru Analysis for Upstream Bio, Inc. (UPB)
Upstream Bio, Inc. (UPB), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q4 2025, a total of 2 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $445,578.5.
Top institutional holders include Cliff Asness and Renaissance Technologies (RenTech).
Institutional sentiment is currently Bullish. This is evidenced by a $460,165.38 net inflow during the quarter.
Recent activity highlights Renaissance Technologies (RenTech) who opened a new position.
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q4 2025)
Guru Consensus (Q4 2025)
FAQs for Upstream Bio, Inc. (UPB)
Major holders include Cliff Asness ($828,158), Renaissance Technologies (RenTech) ($445,260). According to the latest reported data, 2 tracked investment managers collectively hold approximately 46,903 shares.
According to the latest 13F reporting period, sentiment appears Bullish (Net Buying). There was a net inflow of $460,165.38, with 2 managers increasing positions and 0 managers reducing holdings.
No tracked managers reduced or fully exited their positions in UPB during the most recent reporting period.
Yes, 1 managers opened new positions in UPB, and 1 increased their existing holdings. The total reported buy value was $460,165.38.