Guru Ownership Trend
Guru Analysis for Upstream Bio, Inc. (UPB)
Upstream Bio, Inc. (UPB), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q2 2026, a total of 3 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $3.09 M.
Top institutional holders include Cliff Asness and Steven Cohen.
Institutional sentiment is currently Bullish. This is evidenced by a $5.41 M net inflow during the quarter.
Recent activity highlights Cliff Asness who increased their stake by 655.0%.
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q2 2026)
Guru Consensus (Q2 2026)
FAQs for Upstream Bio, Inc. (UPB)
Major holders include Cliff Asness ($3.77 M), Steven Cohen ($3.13 M), Renaissance Technologies (RenTech) ($908,596). According to the latest reported data, 3 tracked investment managers collectively hold approximately 1.13 M shares.
According to the latest 13F reporting period, sentiment appears Bullish (Net Buying). There was a net inflow of $5.41 M, with 3 managers increasing positions and 1 managers reducing holdings.
During the most recent reporting period, 0 managers trimmed their positions, while 1 fully exited UPB. The total reported sell value was $237,708.
Yes, 0 managers opened new positions in UPB, and 3 increased their existing holdings. The total reported buy value was $5.65 M.