Guru Ownership Trend
Guru Analysis for Upstream Bio, Inc. (UPB)
Upstream Bio, Inc. (UPB), a key player in the Healthcare sector, continues to attract institutional attention.
As of Q1 2026, a total of 4 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $2.17 M.
Top institutional holders include Steven Cohen and Cliff Asness.
Institutional sentiment is currently Bullish. This is evidenced by a $2.63 M net inflow during the quarter.
Recent activity highlights Renaissance Technologies (RenTech) who increased their stake by 278.7%.
Key Holders
Top 5 by Value
Top 5 by Conviction
Recent Activity Breakdown (Q1 2026)
Guru Consensus (Q1 2026)
FAQs for Upstream Bio, Inc. (UPB)
Major holders include Steven Cohen ($1.6 M), Cliff Asness ($649,539), Renaissance Technologies (RenTech) ($558,900). According to the latest reported data, 4 tracked investment managers collectively hold approximately 338,851 shares.
According to the latest 13F reporting period, sentiment appears Bullish (Net Buying). There was a net inflow of $2.63 M, with 4 managers increasing positions and 0 managers reducing holdings.
No tracked managers reduced or fully exited their positions in UPB during the most recent reporting period.
Yes, 2 managers opened new positions in UPB, and 2 increased their existing holdings. The total reported buy value was $2.63 M.