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Prime Medicine, Inc.

PRME Healthcare
$3.3 $-0.02 (-0.60%)
Market Cap: $584.23 M
Gurus Holding
5
Popularity Rank
#1776
% of Shares Held
4.23%
Net Activity (Q4 2025)
-$329,080.9

Guru Ownership Trend

Guru Analysis for Prime Medicine, Inc. (PRME)

Prime Medicine, Inc. (PRME), a key player in the Healthcare sector, continues to attract institutional attention.

As of Q4 2025, a total of 5 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $24.73 M.

Top institutional holders include Catherine Wood and Renaissance Technologies.

Institutional sentiment is currently Slightly Bearish. This is evidenced by a $329,080.9 net outflow during the quarter.

Recent activity highlights Paul Tudor Jones who opened a new position. Conversely, Cliff Asness reduced exposure by 2.4%.

Key Holders

Top 5 by Value

Top 5 by Conviction

Recent Activity Breakdown (Q4 2025)

+$50,276.83
Total Buy Value
New Buys 0
Additions 1
-$379,357.73
Total Sell Value
Reductions 1
Sold Out 0

Guru Consensus (Q4 2025)

Based on recent activity
Net Sellers
1
Net Buyers
1

FAQs for Prime Medicine, Inc. (PRME)

Major holders include Catherine Wood ($18.63 M), Renaissance Technologies ($3.99 M), Louis Moore Bacon ($2.77 M). According to the latest reported data, 5 tracked investment managers collectively hold approximately 7.49 M shares.

According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $329,080.9, with 1 managers increasing positions and 1 managers reducing holdings.

During the most recent reporting period, 1 managers trimmed their positions, while 0 fully exited PRME. The total reported sell value was $379,357.73.

Yes, 0 managers opened new positions in PRME, and 1 increased their existing holdings. The total reported buy value was $50,276.83.

Portfolio Manager % Portfolio Activity Shares Value Report Date
0.12% Reduce -2.0% 5,368,526 $18.63 M Q4 2025
0.01% Add 1.3% 1,149,159 $3.99 M Q4 2025
0.04% 500,000 $2.77 M Q3 2025
0.00% Reduce -2.4% 414,211 $2.29 M Q3 2025
0.00% New Buy 62,981 $348,915 Q3 2025
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