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Apellis Pharmaceuticals, Inc.

APLS Healthcare
$40.38 $-0.01 (-0.02%)
Market Cap: $5.16 B
Gurus Holding
7
Popularity Rank
#1096
% of Shares Held
3.16%
Net Activity (Q4 2025)
-$44.28 M

Guru Ownership Trend

Guru Analysis for Apellis Pharmaceuticals, Inc. (APLS)

Apellis Pharmaceuticals, Inc. (APLS), a key player in the Healthcare sector, continues to attract institutional attention.

As of Q4 2025, a total of 7 Super Investors (Gurus) hold positions in the company, with a combined stake valued at approximately $163.27 M.

Top institutional holders include Cliff Asness and Renaissance Technologies (RenTech).

Institutional sentiment is currently Slightly Bearish. This is evidenced by a $44.28 M net outflow during the quarter.

Recent activity highlights Steven Cohen who increased their stake by 175.3%. Conversely, Jefferies Group reduced exposure by 96.5%.

Key Holders

Top 5 by Value

Top 5 by Conviction

Recent Activity Breakdown (Q4 2025)

+$19.61 M
Total Buy Value
New Buys 2
Additions 2
-$63.89 M
Total Sell Value
Reductions 3
Sold Out 0

Guru Consensus (Q4 2025)

Based on recent activity
Net Sellers
3
Net Buyers
4

FAQs for Apellis Pharmaceuticals, Inc. (APLS)

Major holders include Cliff Asness ($57.19 M), Renaissance Technologies (RenTech) ($15.9 M), Steven Cohen ($15.01 M). According to the latest reported data, 7 tracked investment managers collectively hold approximately 4.04 M shares.

According to the latest 13F reporting period, sentiment appears Bearish (Net Selling). There was a net outflow of $44.28 M, with 4 managers increasing positions and 3 managers reducing holdings.

During the most recent reporting period, 3 managers trimmed their positions, while 0 fully exited APLS. The total reported sell value was $63.89 M.

Yes, 2 managers opened new positions in APLS, and 2 increased their existing holdings. The total reported buy value was $19.61 M.

Portfolio Manager % Portfolio Activity Shares Value Report Date
0.03% Reduce -49.3% 2,276,687 $57.19 M Q4 2025
0.02% Reduce -12.4% 633,058 $15.9 M Q4 2025
0.02% Add 175.3% 597,672 $15.01 M Q4 2025
0.01% New Buy 215,000 $5.4 M Q4 2025
0.02% Add 32.5% 168,455 $4.23 M Q4 2025
0.01% New Buy 143,805 $3.61 M Q4 2025
0.00% Reduce -96.5% 8,718 $218,997 Q4 2025
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