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Renaissance Technologies (RenTech)’s XERS Holdings & Trades

First Buy
Q4 2021
Duration Held
19 Quarters
Largest Add
Q4 2021
+880,194 Shares
Current Position
67,337 Shares
$533,308 Value

Renaissance Technologies (RenTech)'s XERS Position Overview

Renaissance Technologies (RenTech) (via Renaissance Technologies LLC) currently holds 67,337 shares of Xeris Biopharma Holdings, Inc. (XERS) worth $533,308, representing 0.00% of the portfolio. First purchased in 2021-Q4, this medium-term investment has been held for 19 quarters.

Based on 13F filings, Renaissance Technologies (RenTech) has maintained a strategic position in XERS, demonstrating sustained confidence in this investment. Largest addition occurred in Q4 2024, adding 500,120 shares. Largest reduction occurred in Q4 2025, reducing 1 M shares.

Analysis based on 13F filings available since 2013 Q2

Renaissance Technologies (RenTech)'s Xeris Biopharma Holdings (XERS) Holding Value Over Time

Track share changes against reported price movement

Quarterly Xeris Biopharma Holdings (XERS) Trades by Renaissance Technologies (RenTech)

Report Date Bought/Sold (Sh.) % Change Qtr. End Shares Reported Price
Q2 2026 -385,523 Reduce 85.13% 67,337 $7.92
Q1 2026 -166,800 Reduce 26.92% 452,860 $5.80
Q4 2025 -1 M Reduce 61.82% 619,660 $7.85
Q3 2025 -432,500 Reduce 21.04% 1.62 M $8.14
Q2 2025 -107,300 Reduce 4.96% 2.06 M $4.67
Q1 2025 +63,800 Add 3.04% 2.16 M $5.49
Q4 2024 +500,120 Add 31.28% 2.1 M $3.39
Q3 2024 +247,080 Add 18.28% 1.6 M $2.85
Q2 2024 +342,300 Add 33.91% 1.35 M $2.25
Q1 2024 -372,300 Reduce 26.95% 1.01 M $2.21
Q4 2023 +359,600 Add 35.18% 1.38 M $2.35
Q3 2023 +163,346 Add 19.02% 1.02 M $1.86
Q2 2023 +254,800 Add 42.19% 858,694 $0.00
Q1 2023 +105,400 Add 21.14% 603,894 $0.00
Q4 2022 -51,200 Reduce 9.31% 498,494 $0.00
Q3 2022 -94,000 Reduce 14.60% 549,694 $1.56
Q2 2022 -49,300 Reduce 7.11% 643,694 $1.54
Q1 2022 -187,200 Reduce 21.27% 692,994 $2.56
Q4 2021 +880,194 New Buy 880,194 $2.93

Renaissance Technologies (RenTech)'s Xeris Biopharma Holdings Investment FAQs

Renaissance Technologies (RenTech) first purchased Xeris Biopharma Holdings, Inc. (XERS) in Q4 2021, acquiring 880,194 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.

Renaissance Technologies (RenTech) has held Xeris Biopharma Holdings, Inc. (XERS) for 19 quarters since Q4 2021.

Renaissance Technologies (RenTech)'s largest addition to Xeris Biopharma Holdings, Inc. (XERS) was in Q4 2021, adding 880,194 shares worth $2.58 M.

According to the latest 13F filing for Q2 2026, Renaissance Technologies (RenTech)'s firm, Renaissance Technologies LLC, owns 67,337 shares of Xeris Biopharma Holdings, Inc. (XERS), valued at approximately $533,308.

As of the Q2 2026 filing, Xeris Biopharma Holdings, Inc. (XERS) represents approximately 0.00% of Renaissance Technologies (RenTech)'s publicly disclosed stock portfolio, making it one of their key holdings.

Renaissance Technologies (RenTech)'s peak holding in Xeris Biopharma Holdings, Inc. (XERS) was 2,162,640 shares, as reported at the end of Q1 2025.