Renaissance Technologies's SRPT Position Overview
Renaissance Technologies (via Renaissance Technologies LLC) currently holds 2.65 M shares of Sarepta Therapeutics, Inc. (SRPT) worth $51.07 M, representing 0.07% of the portfolio. First purchased in 2014-Q4, this long-term strategic position has been held for 44 quarters.
Based on 13F filings since 2013, Renaissance Technologies has maintained a long-term strategic position in SRPT, representing a significant commitment to this investment thesis. Largest addition occurred in Q3 2025, adding 2.03 M shares. Largest reduction occurred in Q3 2018, reducing 387,500 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies's Sarepta Therapeutics (SRPT) Holding Value Over Time
Track share changes against reported price movement
Quarterly Sarepta Therapeutics (SRPT) Trades by Renaissance Technologies
| Period | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q4 2014 | +164,278 | New Buy | 164,278 | $14.47 |
| Q1 2015 | +232,261 | Add 141.38% | 396,539 | $13.28 |
| Q2 2015 | -101,361 | Reduce 25.56% | 295,178 | $30.43 |
| Q3 2015 | +212,560 | Add 72.01% | 507,738 | $32.11 |
| Q4 2015 | -319,160 | Reduce 62.86% | 188,578 | $38.58 |
| Q1 2016 | -188,578 | Sold Out | 188,578 | $0.00 |
| Q4 2016 | +49,078 | New Buy | 49,078 | $27.43 |
| Q1 2017 | +37,000 | Add 75.39% | 86,078 | $29.60 |
| Q2 2017 | -86,078 | Sold Out | 86,078 | $0.00 |
| Q1 2018 | +255,778 | New Buy | 255,778 | $74.09 |
| Q2 2018 | +239,700 | Add 93.71% | 495,478 | $132.18 |
| Q3 2018 | -387,500 | Reduce 78.21% | 107,978 | $161.51 |
| Q4 2018 | -107,978 | Sold Out | 107,978 | $0.00 |
| Q2 2019 | +92,878 | New Buy | 92,878 | $151.95 |
| Q3 2019 | +255,200 | Add 274.77% | 348,078 | $75.32 |
| Q4 2019 | -348,078 | Sold Out | 348,078 | $0.00 |
| Q1 2020 | +79,678 | New Buy | 79,678 | $97.82 |
| Q2 2020 | +376,800 | Add 472.90% | 456,478 | $160.34 |
| Q3 2020 | -299,900 | Reduce 65.70% | 156,578 | $140.43 |
| Q4 2020 | -156,578 | Sold Out | 156,578 | $0.00 |
| Q2 2021 | +127,978 | New Buy | 127,978 | $77.74 |
| Q3 2021 | -119,478 | Reduce 93.36% | 8,500 | $92.47 |
| Q4 2021 | +227,078 | Add 2671.51% | 235,578 | $90.05 |
| Q1 2022 | -86,778 | Reduce 36.84% | 148,800 | $78.12 |
| Q2 2022 | +244,478 | Add 164.30% | 393,278 | $74.96 |
| Q3 2022 | +490,900 | Add 124.82% | 884,178 | $110.54 |
| Q4 2022 | -165,300 | Reduce 18.70% | 718,878 | $0.13 |
| Q1 2023 | +87,600 | Add 12.19% | 806,478 | $0.14 |
| Q2 2023 | -164,400 | Reduce 20.38% | 642,078 | $0.11 |
| Q3 2023 | +40,800 | Add 6.35% | 682,878 | $121.22 |
| Q4 2023 | -119,900 | Reduce 17.56% | 562,978 | $96.43 |
| Q1 2024 | -172,700 | Reduce 30.68% | 390,278 | $129.46 |
| Q2 2024 | -38,278 | Reduce 9.81% | 352,000 | $158.00 |
| Q3 2024 | -121,522 | Reduce 34.52% | 230,478 | $124.89 |
| Q4 2024 | -230,478 | Sold Out | 230,478 | $0.00 |
| Q2 2025 | +624,478 | New Buy | 624,478 | $17.10 |
| Q3 2025 | +2.03 M | Add 324.38% | 2.65 M | $19.27 |
Renaissance Technologies's Sarepta Therapeutics Investment FAQs
Renaissance Technologies first purchased Sarepta Therapeutics, Inc. (SRPT) in Q4 2014, acquiring 164,278 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies has held Sarepta Therapeutics, Inc. (SRPT) for 44 quarters since Q4 2014. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies's largest addition to Sarepta Therapeutics, Inc. (SRPT) was in Q3 2025, adding 2,650,178 shares worth $51.07 M. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
According to the latest 13F filing for Q3 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 2,650,178 shares of Sarepta Therapeutics, Inc. (SRPT), valued at approximately $51.07 M. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
As of the Q3 2025 filing, Sarepta Therapeutics, Inc. (SRPT) represents approximately 0.07% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies's peak holding in Sarepta Therapeutics, Inc. (SRPT) was 2,650,178 shares, as reported at the end of Q3 2025. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.