Renaissance Technologies (RenTech)'s SRPT Position Overview
Renaissance Technologies (RenTech) (via Renaissance Technologies LLC) currently holds 1.67 M shares of Sarepta Therapeutics, Inc. (SRPT) worth $36.23 M, representing 0.06% of the portfolio. First purchased in 2014-Q4, this long-term strategic position has been held for 39 quarters.
Based on 13F filings, Renaissance Technologies (RenTech) has maintained a strategic position in SRPT, demonstrating sustained confidence in this investment. Largest addition occurred in Q3 2025, adding 2.03 M shares. Largest reduction occurred in Q4 2025, reducing 1.49 M shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies (RenTech)'s Sarepta Therapeutics (SRPT) Holding Value Over Time
Track share changes against reported price movement
Quarterly Sarepta Therapeutics (SRPT) Trades by Renaissance Technologies (RenTech)
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q1 2026 | +505,500 | Add 43.59% | 1.67 M | $21.76 |
| Q4 2025 | -1.49 M | Reduce 56.25% | 1.16 M | $21.52 |
| Q3 2025 | +2.03 M | Add 324.38% | 2.65 M | $19.27 |
| Q2 2025 | +624,478 | New Buy | 624,478 | $17.10 |
| Q4 2024 | -230,478 | Sold Out | 0 | $0.00 |
| Q3 2024 | -121,522 | Reduce 34.52% | 230,478 | $124.89 |
| Q2 2024 | -38,278 | Reduce 9.81% | 352,000 | $158.00 |
| Q1 2024 | -172,700 | Reduce 30.68% | 390,278 | $129.46 |
| Q4 2023 | -119,900 | Reduce 17.56% | 562,978 | $96.43 |
| Q3 2023 | +40,800 | Add 6.35% | 682,878 | $121.22 |
| Q2 2023 | -164,400 | Reduce 20.38% | 642,078 | $0.11 |
| Q1 2023 | +87,600 | Add 12.19% | 806,478 | $0.14 |
| Q4 2022 | -165,300 | Reduce 18.70% | 718,878 | $0.13 |
| Q3 2022 | +490,900 | Add 124.82% | 884,178 | $110.54 |
| Q2 2022 | +244,478 | Add 164.30% | 393,278 | $74.96 |
| Q1 2022 | -86,778 | Reduce 36.84% | 148,800 | $78.12 |
| Q4 2021 | +227,078 | Add 2671.51% | 235,578 | $90.05 |
| Q3 2021 | -119,478 | Reduce 93.36% | 8,500 | $92.47 |
| Q2 2021 | +127,978 | New Buy | 127,978 | $77.74 |
| Q4 2020 | -156,578 | Sold Out | 0 | $0.00 |
| Q3 2020 | -299,900 | Reduce 65.70% | 156,578 | $140.43 |
| Q2 2020 | +376,800 | Add 472.90% | 456,478 | $160.34 |
| Q1 2020 | +79,678 | New Buy | 79,678 | $97.82 |
| Q4 2019 | -348,078 | Sold Out | 0 | $0.00 |
| Q3 2019 | +255,200 | Add 274.77% | 348,078 | $75.32 |
| Q2 2019 | +92,878 | New Buy | 92,878 | $151.95 |
| Q4 2018 | -107,978 | Sold Out | 0 | $0.00 |
| Q3 2018 | -387,500 | Reduce 78.21% | 107,978 | $161.51 |
| Q2 2018 | +239,700 | Add 93.71% | 495,478 | $132.18 |
| Q1 2018 | +255,778 | New Buy | 255,778 | $74.09 |
| Q2 2017 | -86,078 | Sold Out | 0 | $0.00 |
| Q1 2017 | +37,000 | Add 75.39% | 86,078 | $29.60 |
| Q4 2016 | +49,078 | New Buy | 49,078 | $27.43 |
| Q1 2016 | -188,578 | Sold Out | 0 | $0.00 |
| Q4 2015 | -319,160 | Reduce 62.86% | 188,578 | $38.58 |
| Q3 2015 | +212,560 | Add 72.01% | 507,738 | $32.11 |
| Q2 2015 | -101,361 | Reduce 25.56% | 295,178 | $30.43 |
| Q1 2015 | +232,261 | Add 141.38% | 396,539 | $13.28 |
| Q4 2014 | +164,278 | New Buy | 164,278 | $14.47 |
Renaissance Technologies (RenTech)'s Sarepta Therapeutics Investment FAQs
Renaissance Technologies (RenTech) first purchased Sarepta Therapeutics, Inc. (SRPT) in Q4 2014, acquiring 164,278 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies (RenTech) has held Sarepta Therapeutics, Inc. (SRPT) for 39 quarters since Q4 2014.
Renaissance Technologies (RenTech)'s largest addition to Sarepta Therapeutics, Inc. (SRPT) was in Q3 2025, adding 2,650,178 shares worth $51.07 M.
According to the latest 13F filing for Q1 2026, Renaissance Technologies (RenTech)'s firm, Renaissance Technologies LLC, owns 1,665,078 shares of Sarepta Therapeutics, Inc. (SRPT), valued at approximately $36.23 M.
As of the Q1 2026 filing, Sarepta Therapeutics, Inc. (SRPT) represents approximately 0.06% of Renaissance Technologies (RenTech)'s publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies (RenTech)'s peak holding in Sarepta Therapeutics, Inc. (SRPT) was 2,650,178 shares, as reported at the end of Q3 2025.