Renaissance Technologies's KRYS Position Overview
Renaissance Technologies (via Renaissance Technologies LLC) currently holds 3,300 shares of Krystal Biotech, Inc. (KRYS) worth $813,582, representing 0.00% of the portfolio. First purchased in 2018-Q3, this medium-term investment has been held for 18 quarters.
Based on 13F filings, Renaissance Technologies has maintained a strategic position in KRYS, demonstrating sustained confidence in this investment. Largest addition occurred in Q2 2025, adding 78,600 shares. Largest reduction occurred in Q3 2025, reducing 89,800 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies's Krystal Biotech (KRYS) Holding Value Over Time
Track share changes against reported price movement
Quarterly Krystal Biotech (KRYS) Trades by Renaissance Technologies
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q4 2025 | +3,300 | New Buy | 3,300 | $246.54 |
| Q3 2025 | -89,800 | Sold Out | 0 | $0.00 |
| Q2 2025 | +78,600 | Add 701.79% | 89,800 | $137.46 |
| Q1 2025 | +300 | Add 2.75% | 11,200 | $180.30 |
| Q4 2024 | -3,500 | Reduce 24.31% | 10,900 | $156.66 |
| Q3 2024 | +14,400 | New Buy | 14,400 | $182.03 |
| Q2 2024 | -24,700 | Sold Out | 0 | $0.00 |
| Q1 2024 | +24,700 | New Buy | 24,700 | $177.94 |
| Q4 2021 | -33,300 | Sold Out | 0 | $0.00 |
| Q3 2021 | +33,300 | New Buy | 33,300 | $52.22 |
| Q4 2020 | -19,600 | Sold Out | 0 | $0.00 |
| Q3 2020 | -41,800 | Reduce 68.08% | 19,600 | $43.06 |
| Q2 2020 | +55,400 | Add 923.33% | 61,400 | $41.42 |
| Q1 2020 | +6,000 | New Buy | 6,000 | $43.17 |
| Q2 2019 | -30,800 | Sold Out | 0 | $0.00 |
| Q1 2019 | -11,100 | Reduce 26.49% | 30,800 | $32.89 |
| Q4 2018 | -8,800 | Reduce 17.36% | 41,900 | $20.79 |
| Q3 2018 | +50,700 | New Buy | 50,700 | $17.57 |
Renaissance Technologies's Krystal Biotech Investment FAQs
Renaissance Technologies first purchased Krystal Biotech, Inc. (KRYS) in Q3 2018, acquiring 50,700 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies has held Krystal Biotech, Inc. (KRYS) for 18 quarters since Q3 2018.
Renaissance Technologies's largest addition to Krystal Biotech, Inc. (KRYS) was in Q2 2025, adding 89,800 shares worth $12.34 M.
According to the latest 13F filing for Q4 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 3,300 shares of Krystal Biotech, Inc. (KRYS), valued at approximately $813,582.
As of the Q4 2025 filing, Krystal Biotech, Inc. (KRYS) represents approximately 0.00% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies's peak holding in Krystal Biotech, Inc. (KRYS) was 89,800 shares, as reported at the end of Q2 2025.