Renaissance Technologies (RenTech)'s KPTI Position Overview
Renaissance Technologies (RenTech) (via Renaissance Technologies LLC) currently holds 105,414 shares of Karyopharm Therapeutics Inc. (KPTI) worth $587,156, representing 0.00% of the portfolio. First purchased in 2025-Q1, this short-term holding has been held for 5 quarters.
Based on 13F filings, Renaissance Technologies (RenTech) has maintained this position in KPTI for several quarters, showing initial confidence in the investment. Largest addition occurred in Q1 2026, adding 45,500 shares. Largest reduction occurred in Q4 2025, reducing 4,800 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies (RenTech)'s Karyopharm Therapeutics (KPTI) Holding Value Over Time
Track share changes against reported price movement
Quarterly Karyopharm Therapeutics (KPTI) Trades by Renaissance Technologies (RenTech)
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q1 2026 | +45,500 | Add 75.94% | 105,414 | $5.57 |
| Q4 2025 | -4,800 | Reduce 7.42% | 59,914 | $7.36 |
| Q3 2025 | -1,100 | Reduce 1.67% | 64,714 | $6.54 |
| Q2 2025 | +4,600 | Add 7.51% | 65,814 | $4.31 |
| Q1 2025 | +61,214 | New Buy | 61,214 | $3.74 |
Renaissance Technologies (RenTech)'s Karyopharm Therapeutics Investment FAQs
Renaissance Technologies (RenTech) first purchased Karyopharm Therapeutics Inc. (KPTI) in Q1 2025, acquiring 61,214 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies (RenTech) has held Karyopharm Therapeutics Inc. (KPTI) for 5 quarters since Q1 2025.
Renaissance Technologies (RenTech)'s largest addition to Karyopharm Therapeutics Inc. (KPTI) was in Q1 2025, adding 61,214 shares worth $228,940.
According to the latest 13F filing for Q1 2026, Renaissance Technologies (RenTech)'s firm, Renaissance Technologies LLC, owns 105,414 shares of Karyopharm Therapeutics Inc. (KPTI), valued at approximately $587,156.
As of the Q1 2026 filing, Karyopharm Therapeutics Inc. (KPTI) represents approximately 0.00% of Renaissance Technologies (RenTech)'s publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies (RenTech)'s peak holding in Karyopharm Therapeutics Inc. (KPTI) was 105,414 shares, as reported at the end of Q1 2026.