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Renaissance Technologies’s INSM Holdings & Trades

First Buy
Q2 2014
Duration Held
19 Quarters
Largest Add
Q2 2025
+308,687 Shares
Current Position
25,900 Shares
$4.51 M Value

Renaissance Technologies's INSM Position Overview

Renaissance Technologies (via Renaissance Technologies LLC) currently holds 25,900 shares of Insmed Incorporated (INSM) worth $4.51 M, representing 0.01% of the portfolio. First purchased in 2014-Q2, this medium-term investment has been held for 19 quarters.

Based on 13F filings, Renaissance Technologies has maintained a strategic position in INSM, demonstrating sustained confidence in this investment. Largest addition occurred in Q2 2025, adding 308,687 shares. Largest reduction occurred in Q4 2025, reducing 326,987 shares.

Analysis based on 13F filings available since 2013 Q2

Renaissance Technologies's Insmed Incorporated (INSM) Holding Value Over Time

Track share changes against reported price movement

Quarterly Insmed Incorporated (INSM) Trades by Renaissance Technologies

Report Date Bought/Sold (Sh.) % Change Qtr. End Shares Reported Price
Q4 2025 -326,987 Reduce 92.66% 25,900 $174.04
Q3 2025 +44,200 Add 14.32% 352,887 $144.01
Q2 2025 +308,687 New Buy 308,687 $100.64
Q1 2025 -25,287 Sold Out 0 $0.00
Q4 2024 +25,287 New Buy 25,287 $69.04
Q2 2024 -133,987 Sold Out 0 $0.00
Q1 2024 +133,987 New Buy 133,987 $27.13
Q1 2023 -27,300 Sold Out 0 $0.00
Q4 2022 +27,300 New Buy 27,300 $0.02
Q1 2018 -36,487 Sold Out 0 $0.00
Q4 2017 -19,400 Reduce 34.71% 36,487 $31.19
Q3 2017 +55,887 New Buy 55,887 $31.21
Q1 2017 -120,500 Sold Out 0 $0.00
Q4 2016 -77,200 Reduce 39.05% 120,500 $13.23
Q3 2016 +48,400 Add 32.42% 197,700 $14.52
Q2 2016 -34,487 Reduce 18.76% 149,300 $9.86
Q1 2016 +183,787 New Buy 183,787 $12.67
Q3 2014 -48,587 Sold Out 0 $0.00
Q2 2014 +48,587 New Buy 48,587 $19.98

Renaissance Technologies's Insmed Incorporated Investment FAQs

Renaissance Technologies first purchased Insmed Incorporated (INSM) in Q2 2014, acquiring 48,587 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.

Renaissance Technologies has held Insmed Incorporated (INSM) for 19 quarters since Q2 2014.

Renaissance Technologies's largest addition to Insmed Incorporated (INSM) was in Q2 2025, adding 308,687 shares worth $31.07 M.

According to the latest 13F filing for Q4 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 25,900 shares of Insmed Incorporated (INSM), valued at approximately $4.51 M.

As of the Q4 2025 filing, Insmed Incorporated (INSM) represents approximately 0.01% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings.

Renaissance Technologies's peak holding in Insmed Incorporated (INSM) was 352,887 shares, as reported at the end of Q3 2025.