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Renaissance Technologies’s GPCR Holdings & Trades

First Buy
Q2 2023
Duration Held
8 Quarters
Largest Add
Q2 2025
+96,100 Shares
Current Position
115,200 Shares
$8.01 M Value

Renaissance Technologies's GPCR Position Overview

Renaissance Technologies (via Renaissance Technologies LLC) currently holds 115,200 shares of Structure Therapeutics Inc. (GPCR) worth $8.01 M, representing 0.01% of the portfolio. First purchased in 2023-Q2, this short-term holding has been held for 8 quarters.

Based on 13F filings, Renaissance Technologies has maintained this position in GPCR for several quarters, showing initial confidence in the investment. Largest addition occurred in Q2 2025, adding 96,100 shares. Largest reduction occurred in Q4 2025, reducing 38,700 shares.

Analysis based on 13F filings available since 2013 Q2

Renaissance Technologies's Structure Therapeutics (GPCR) Holding Value Over Time

Track share changes against reported price movement

Quarterly Structure Therapeutics (GPCR) Trades by Renaissance Technologies

Report Date Bought/Sold (Sh.) % Change Qtr. End Shares Reported Price
Q2 2023 +32,900 New Buy 32,900 $0.04
Q3 2023 -32,900 Sold Out 0 $0.00
Q2 2024 +35,700 New Buy 35,700 $39.27
Q3 2024 -35,700 Sold Out 0 $0.00
Q1 2025 +15,800 New Buy 15,800 $17.31
Q2 2025 +96,100 Add 608.23% 111,900 $20.74
Q3 2025 +42,000 Add 37.53% 153,900 $28.00
Q4 2025 -38,700 Reduce 25.15% 115,200 $69.55

Renaissance Technologies's Structure Therapeutics Investment FAQs

Renaissance Technologies first purchased Structure Therapeutics Inc. (GPCR) in Q2 2023, acquiring 32,900 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.

Renaissance Technologies has held Structure Therapeutics Inc. (GPCR) for 8 quarters since Q2 2023.

Renaissance Technologies's largest addition to Structure Therapeutics Inc. (GPCR) was in Q2 2025, adding 111,900 shares worth $2.32 M.

According to the latest 13F filing for Q4 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 115,200 shares of Structure Therapeutics Inc. (GPCR), valued at approximately $8.01 M.

As of the Q4 2025 filing, Structure Therapeutics Inc. (GPCR) represents approximately 0.01% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings.

Renaissance Technologies's peak holding in Structure Therapeutics Inc. (GPCR) was 153,900 shares, as reported at the end of Q3 2025.