Renaissance Technologies's EXEL Position Overview
Renaissance Technologies (via Renaissance Technologies LLC) currently holds 15.5M shares of Exelixis, Inc. (EXEL) worth $638.47 M, representing 0.84% of the portfolio. First purchased in 2014-Q2, this long-term strategic position has been held for 46 quarters.
Based on 13F filings since 2013, Renaissance Technologies has maintained a long-term strategic position in EXEL, representing a significant commitment to this investment thesis. Largest addition occurred in Q2 2019, adding 3.9M shares. Largest reduction occurred in Q1 2021, reducing 3.0M shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies's Exelixis (EXEL) Holding Value Over Time
Track share changes against reported price movement
Quarterly Exelixis (EXEL) Trades by Renaissance Technologies
| Period | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q2 2014 | +1.66 M | New Buy | 1.66 M | $3.39 |
| Q3 2014 | -1.66 M | Sold Out | 1.66 M | $0.00 |
| Q4 2014 | +178,033 | New Buy | 178,033 | $1.44 |
| Q1 2015 | -178,033 | Sold Out | 178,033 | $0.00 |
| Q4 2015 | +551,350 | New Buy | 551,350 | $5.64 |
| Q1 2016 | +457,569 | Add 82.99% | 1.01 M | $4.00 |
| Q2 2016 | -1.01 M | Sold Out | 1.01 M | $0.00 |
| Q3 2016 | +1.87 M | New Buy | 1.87 M | $12.79 |
| Q4 2016 | -557,940 | Reduce 29.86% | 1.31 M | $14.91 |
| Q1 2017 | +247,550 | Add 18.89% | 1.56 M | $21.67 |
| Q2 2017 | +881,050 | Add 56.55% | 2.44 M | $24.63 |
| Q3 2017 | +1.36 M | Add 55.74% | 3.8 M | $24.23 |
| Q4 2017 | -716,700 | Reduce 18.87% | 3.08 M | $30.40 |
| Q1 2018 | +70,850 | Add 2.30% | 3.15 M | $22.15 |
| Q2 2018 | +885,000 | Add 28.07% | 4.04 M | $21.52 |
| Q3 2018 | +60,900 | Add 1.51% | 4.1 M | $17.72 |
| Q4 2018 | +1.82 M | Add 44.43% | 5.92 M | $19.67 |
| Q1 2019 | +3.65 M | Add 61.58% | 9.57 M | $23.80 |
| Q2 2019 | +3.89 M | Add 40.66% | 13.45 M | $21.37 |
| Q3 2019 | +1.4 M | Add 10.37% | 14.85 M | $17.68 |
| Q4 2019 | +3.1 M | Add 20.91% | 17.95 M | $17.62 |
| Q1 2020 | +2.12 M | Add 11.79% | 20.07 M | $17.22 |
| Q2 2020 | +2.94 M | Add 14.63% | 23.01 M | $23.74 |
| Q3 2020 | -341,300 | Reduce 1.48% | 22.67 M | $24.45 |
| Q4 2020 | -982,959 | Reduce 4.34% | 21.68 M | $20.07 |
| Q1 2021 | -3.05 M | Reduce 14.07% | 18.63 M | $22.59 |
| Q2 2021 | -550,300 | Reduce 2.95% | 18.08 M | $18.22 |
| Q3 2021 | -535,000 | Reduce 2.96% | 17.55 M | $21.14 |
| Q4 2021 | -446,723 | Reduce 2.55% | 17.1 M | $18.28 |
| Q1 2022 | -238,500 | Reduce 1.39% | 16.86 M | $22.67 |
| Q2 2022 | +921,659 | Add 5.47% | 17.78 M | $20.82 |
| Q3 2022 | -1.75 M | Reduce 9.86% | 16.03 M | $15.68 |
| Q4 2022 | -1.07 M | Reduce 6.67% | 14.96 M | $0.02 |
| Q1 2023 | +318,300 | Add 2.13% | 15.28 M | $0.02 |
| Q2 2023 | -631,800 | Reduce 4.13% | 14.65 M | $0.02 |
| Q3 2023 | +569,327 | Add 3.89% | 15.22 M | $21.85 |
| Q4 2023 | +398,800 | Add 2.62% | 15.62 M | $23.99 |
| Q1 2024 | -514,000 | Reduce 3.29% | 15.1 M | $23.73 |
| Q2 2024 | +61,350 | Add 0.41% | 15.16 M | $22.47 |
| Q3 2024 | +196,850 | Add 1.30% | 15.36 M | $25.95 |
| Q4 2024 | -64,051 | Reduce 0.42% | 15.3 M | $33.30 |
| Q1 2025 | -471,600 | Reduce 3.08% | 14.82 M | $36.92 |
| Q2 2025 | +995,500 | Add 6.72% | 15.82 M | $44.08 |
| Q3 2025 | -360,499 | Reduce 2.28% | 15.46 M | $41.30 |
Renaissance Technologies's Exelixis Investment FAQs
Renaissance Technologies first purchased Exelixis, Inc. (EXEL) in Q2 2014, acquiring 1,658,150 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies has held Exelixis, Inc. (EXEL) for 46 quarters since Q2 2014. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies's largest addition to Exelixis, Inc. (EXEL) was in Q2 2019, adding 13,454,473 shares worth $287.52 M. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
According to the latest 13F filing for Q3 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 15,459,266 shares of Exelixis, Inc. (EXEL), valued at approximately $638.47 M. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
As of the Q3 2025 filing, Exelixis, Inc. (EXEL) represents approximately 0.84% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies's peak holding in Exelixis, Inc. (EXEL) was 23,006,910 shares, as reported at the end of Q2 2020. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.