Renaissance Technologies's XBI Position Overview
Renaissance Technologies (via Renaissance Technologies LLC) currently holds 41,100 shares of State Street SPDR S&P Biotech ETF (XBI) worth $5.01 M, representing 0.01% of the portfolio. First purchased in 2020-Q2, this medium-term investment has been held for 13 quarters.
Based on 13F filings, Renaissance Technologies has maintained a strategic position in XBI, demonstrating sustained confidence in this investment. Largest addition occurred in Q1 2022, adding 52,300 shares. Largest reduction occurred in Q3 2025, reducing 48,800 shares.
Analysis based on 13F filings available since 2013 Q2
Renaissance Technologies's State Street SPDR S&P Biotech ETF (XBI) Holding Value Over Time
Track share changes against reported price movement
Quarterly State Street SPDR S&P Biotech ETF (XBI) Trades by Renaissance Technologies
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q2 2020 | +26,900 | New Buy | 26,900 | $111.93 |
| Q3 2020 | -26,900 | Sold Out | 0 | $0.00 |
| Q1 2022 | +52,300 | New Buy | 52,300 | $89.89 |
| Q2 2022 | -41,100 | Reduce 78.59% | 11,200 | $74.29 |
| Q3 2022 | -7,100 | Reduce 63.39% | 4,100 | $79.27 |
| Q4 2022 | -4,100 | Sold Out | 0 | $0.00 |
| Q1 2023 | +18,200 | New Buy | 18,200 | $0.08 |
| Q2 2023 | -18,200 | Sold Out | 0 | $0.00 |
| Q4 2024 | +5,500 | New Buy | 5,500 | $90.06 |
| Q1 2025 | -5,500 | Sold Out | 0 | $0.00 |
| Q2 2025 | +48,800 | New Buy | 48,800 | $82.93 |
| Q3 2025 | -48,800 | Sold Out | 0 | $0.00 |
| Q4 2025 | +41,100 | New Buy | 41,100 | $121.93 |
Renaissance Technologies's State Street SPDR S&P Biotech ETF Investment FAQs
Renaissance Technologies first purchased State Street SPDR S&P Biotech ETF (XBI) in Q2 2020, acquiring 26,900 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Renaissance Technologies has held State Street SPDR S&P Biotech ETF (XBI) for 13 quarters since Q2 2020.
Renaissance Technologies's largest addition to State Street SPDR S&P Biotech ETF (XBI) was in Q1 2022, adding 52,300 shares worth $4.7 M.
According to the latest 13F filing for Q4 2025, Renaissance Technologies's firm, Renaissance Technologies LLC, owns 41,100 shares of State Street SPDR S&P Biotech ETF (XBI), valued at approximately $5.01 M.
As of the Q4 2025 filing, State Street SPDR S&P Biotech ETF (XBI) represents approximately 0.01% of Renaissance Technologies's publicly disclosed stock portfolio, making it one of their key holdings.
Renaissance Technologies's peak holding in State Street SPDR S&P Biotech ETF (XBI) was 52,300 shares, as reported at the end of Q1 2022.