S&P 500: 681.75 +0.1% NASDAQ 100: 601.92 +0.2% Dow Jones: 495.28 +0.1%

Jefferies Group’s GPCR Holdings & Trades

First Buy
Q1 2024
Duration Held
7 Quarters
Largest Add
Q3 2025
+170,345 Shares
Current Position
102,993 Shares
$7.16 M Value

Jefferies Group's GPCR Position Overview

Jefferies Group (via Jefferies Financial Group Inc.) currently holds 102,993 shares of Structure Therapeutics Inc. (GPCR) worth $7.16 M, representing 0.04% of the portfolio. First purchased in 2024-Q1, this short-term holding has been held for 7 quarters.

Based on 13F filings, Jefferies Group has maintained this position in GPCR for several quarters, showing initial confidence in the investment. Largest addition occurred in Q3 2025, adding 170,345 shares. Largest reduction occurred in Q4 2025, reducing 67,352 shares.

Analysis based on 13F filings available since 2013 Q2

Jefferies Group's Structure Therapeutics (GPCR) Holding Value Over Time

Track share changes against reported price movement

Quarterly Structure Therapeutics (GPCR) Trades by Jefferies Group

Report Date Bought/Sold (Sh.) % Change Qtr. End Shares Reported Price
Q1 2024 +2,000 New Buy 2,000 $42.86
Q2 2024 -2,000 Sold Out 0 $0.00
Q3 2024 +7,000 New Buy 7,000 $43.89
Q4 2024 -5,000 Reduce 71.43% 2,000 $27.12
Q1 2025 -2,000 Sold Out 0 $0.00
Q3 2025 +170,345 New Buy 170,345 $28.00
Q4 2025 -67,352 Reduce 39.54% 102,993 $69.55

Jefferies Group's Structure Therapeutics Investment FAQs

Jefferies Group first purchased Structure Therapeutics Inc. (GPCR) in Q1 2024, acquiring 2,000 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.

Jefferies Group has held Structure Therapeutics Inc. (GPCR) for 7 quarters since Q1 2024.

Jefferies Group's largest addition to Structure Therapeutics Inc. (GPCR) was in Q3 2025, adding 170,345 shares worth $4.77 M.

According to the latest 13F filing for Q4 2025, Jefferies Group's firm, Jefferies Financial Group Inc., owns 102,993 shares of Structure Therapeutics Inc. (GPCR), valued at approximately $7.16 M.

As of the Q4 2025 filing, Structure Therapeutics Inc. (GPCR) represents approximately 0.04% of Jefferies Group's publicly disclosed stock portfolio, making it one of their key holdings.

Jefferies Group's peak holding in Structure Therapeutics Inc. (GPCR) was 170,345 shares, as reported at the end of Q3 2025.