Cliff Asness's OPK Position Overview
Cliff Asness (via Aqr Capital Management LLC) currently holds 2.03 M shares of OPKO Health, Inc. (OPK) worth $2.55 M, representing 0.00% of the portfolio. First purchased in 2013-Q2, this long-term strategic position has been held for 44 quarters.
Based on 13F filings since 2013, Cliff Asness has maintained a long-term strategic position in OPK, representing a significant commitment to this investment thesis. Largest addition occurred in Q3 2025, adding 1.94 M shares. Largest reduction occurred in Q1 2016, reducing 1.12 M shares.
Analysis based on 13F filings available since 2013 Q2
Cliff Asness's OPKO Health (OPK) Holding Value Over Time
Track share changes against reported price movement
Quarterly OPKO Health (OPK) Trades by Cliff Asness
| Report Date | Bought/Sold (Sh.) | % Change | Qtr. End Shares | Reported Price |
|---|---|---|---|---|
| Q4 2025 | -846,459 | Reduce 29.46% | 2.03 M | $1.26 |
| Q3 2025 | +1.94 M | Add 207.02% | 2.87 M | $1.55 |
| Q2 2025 | -673,006 | Reduce 41.83% | 935,900 | $1.32 |
| Q1 2025 | +1.32 M | Add 466.68% | 1.61 M | $1.66 |
| Q4 2024 | +206,768 | Add 268.01% | 283,918 | $1.47 |
| Q3 2024 | -2,689 | Reduce 3.37% | 77,150 | $1.49 |
| Q2 2024 | -19,600 | Reduce 19.71% | 79,839 | $1.25 |
| Q1 2024 | -227,216 | Reduce 69.56% | 99,439 | $1.20 |
| Q4 2023 | +151,025 | Add 85.99% | 326,655 | $1.51 |
| Q3 2023 | +175,630 | New Buy | 175,630 | $1.60 |
| Q2 2023 | -40,772 | Sold Out | 0 | $0.00 |
| Q1 2023 | -37,566 | Reduce 47.95% | 40,772 | $1.46 |
| Q4 2022 | -252,911 | Reduce 76.35% | 78,338 | $1.25 |
| Q3 2022 | +162,396 | Add 96.18% | 331,249 | $1.89 |
| Q2 2022 | -426,126 | Reduce 71.62% | 168,853 | $2.53 |
| Q1 2022 | +440,720 | Add 285.70% | 594,979 | $3.44 |
| Q4 2021 | -146,248 | Reduce 48.67% | 154,259 | $4.81 |
| Q3 2021 | -144,214 | Reduce 32.43% | 300,507 | $3.65 |
| Q2 2021 | -158,916 | Reduce 26.33% | 444,721 | $4.05 |
| Q1 2021 | -194,491 | Reduce 24.37% | 603,637 | $4.29 |
| Q4 2020 | +205,595 | Add 34.70% | 798,128 | $3.95 |
| Q3 2020 | +592,533 | New Buy | 592,533 | $3.69 |
| Q3 2019 | -171,725 | Sold Out | 0 | $0.00 |
| Q2 2019 | +171,725 | New Buy | 171,725 | $2.44 |
| Q1 2019 | -15,688 | Sold Out | 0 | $0.00 |
| Q4 2018 | +15,688 | New Buy | 15,688 | $3.00 |
| Q3 2018 | -13,899 | Sold Out | 0 | $0.00 |
| Q2 2018 | +13,899 | New Buy | 13,899 | $4.68 |
| Q1 2017 | -11,275 | Sold Out | 0 | $0.00 |
| Q4 2016 | +11,275 | New Buy | 11,275 | $9.31 |
| Q3 2016 | -256,222 | Sold Out | 0 | $0.00 |
| Q2 2016 | +38,748 | Add 17.82% | 256,222 | $9.34 |
| Q1 2016 | -1.12 M | Reduce 83.70% | 217,474 | $10.39 |
| Q4 2015 | -243,603 | Reduce 15.44% | 1.33 M | $10.05 |
| Q3 2015 | +1.48 M | Add 1446.10% | 1.58 M | $8.41 |
| Q2 2015 | +11,235 | Add 12.37% | 102,035 | $16.08 |
| Q1 2015 | +2,300 | Add 2.60% | 90,800 | $14.17 |
| Q4 2014 | -744 | Reduce 0.83% | 88,500 | $9.99 |
| Q3 2014 | -1,100 | Reduce 1.22% | 89,244 | $8.50 |
| Q2 2014 | -4,585 | Reduce 4.83% | 90,344 | $8.84 |
| Q1 2014 | -24,300 | Reduce 20.38% | 94,929 | $9.32 |
| Q4 2013 | -27,316 | Reduce 18.64% | 119,229 | $8.44 |
| Q3 2013 | +112,600 | Add 331.71% | 146,545 | $8.81 |
| Q2 2013 | +33,945 | Add 0.00% | 33,945 | $7.10 |
Cliff Asness's OPKO Health Investment FAQs
Cliff Asness first purchased OPKO Health, Inc. (OPK) in Q2 2013, acquiring 33,945 shares, as reported in their 13F filing for that period. Note: Analysis reflects filings available since Q2 2013; earlier records may be incomplete.
Cliff Asness has held OPKO Health, Inc. (OPK) for 44 quarters since Q2 2013.
Cliff Asness's largest addition to OPKO Health, Inc. (OPK) was in Q3 2025, adding 2,873,416 shares worth $4.45 M.
According to the latest 13F filing for Q4 2025, Cliff Asness's firm, Aqr Capital Management LLC, owns 2,026,957 shares of OPKO Health, Inc. (OPK), valued at approximately $2.55 M.
As of the Q4 2025 filing, OPKO Health, Inc. (OPK) represents approximately 0.00% of Cliff Asness's publicly disclosed stock portfolio, making it one of their key holdings.
Cliff Asness's peak holding in OPKO Health, Inc. (OPK) was 2,873,416 shares, as reported at the end of Q3 2025.